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(609) 336-7518

09AM to 05PM EST

The Efficacy of Semaglutide for Weight Loss in Non-Diabetics

Have you had trouble losing weight despite trying different diets and workout plans? If so, you’re not alone. Millions of people around the world are overweight or obese, which is a significant health problem. Fortunately, a new medicine called semaglutide is gaining popularity as a potential weight loss aid.

This blog post will discuss semaglutide, how it works, how it can help people without diabetes lose weight, and more.

Understanding Semaglutide

Semaglutide is a glucagon-like peptide-1 GLP-1 receptor agonist. Researchers first developed it to treat type 2 diabetes mellitus (T2DM), but the latest investigation shows that it may also help people without diabetes keep their weight in check.

The United States Food and Drug Administration (FDA) has approved semaglutide specifically for obesity.

How Does Semaglutide Help with Weight Loss?

Semaglutide for weight loss in non diabetics works by mimicking the actions of the GLP-1 hormone, which the body naturally makes. This hormone is essential for controlling hunger, breaking down glucose, and producing insulin.

Here are several ways that semaglutide helps people lose weight:

  • Appetite and Hunger Control: By changing the brain receptors that control hunger, Semaglutide makes people feel much less hungry. It causes them to eat fewer calories. It also causes you to burn more fat and use more energy, which is crucial for eliminating extra body fat.
  • Metabolic Enhancements: Semaglutide increases insulin, which is dependent on glucose, and lowers glucagon release. That aids in maintaining blood sugar. It also increases energy expenditure and fat oxidation, which is crucial for burning excess body fat.
  • Impact on Eating Behaviors: Semaglutide can change your eating habits. It can make you less interested in fatty, high-calorie foods. It can also reduce your overall cravings for food. If you change the foods you like to eat, you’ll lose weight, keep it off, and live longer.

A study showed that semaglutide can help people lose weight. Over 68 weeks of treatment, some patients lost up to 20% of their body weight. However, it’s essential to know that weight can return if you stop treatment, so you need to keep managing it.

Semaglutide for Weight Loss in Non-Diabetics

Dosages and Administration Guidelines

How to dose semaglutide for weight loss? Doctors typically start semaglutide for weight loss at 0.25 mg per week and gradually increase it. The maintenance dose is usually 2.4 mg per week.

This slow increase in amount helps reduce the chance of adverse reactions and gives the body time to get used to the drug. The semaglutide for weight loss in non diabetics dosage schedule is as follows:

  • For the first four weeks, start with 0.25 mg once per week.
  • For the next four weeks, increase to 0.5 mg once weekly.
  • Raise the dose to 1 mg once a week and then to 1.7 mg.
  • Reach a sustaining dose of 2.4 mg once a week.

The best way to take semaglutide is subcutaneously (under the skin) in the stomach, thighs, or upper arm area every week. To avoid skin irritation, inject at different locations and with a new needle each time. It can help you maintain hygiene and reduce the likelihood of infection.

Semaglutide for Weight Loss in Non-Diabetics

How Long to Use Semaglutide for Weight Loss?

How long a person takes semaglutide to lose weight depends on many factors, including how much they want to lose, how well they respond to the medicine, and their starting weight.

Within the first three months of treatment, patients can experience a mean weight loss of approximately 6.7 kg (5.9% of their body weight). Extending the treatment to 6 months can increase the mean weight loss to 12.3 kg (10.9% of body weight). These results show that semaglutide helps individuals lose weight in the long run.

It would help if you determined the specific length of treatment in consultation with a healthcare provider. As each patient’s semaglutide treatment plan will be different.

It will depend on their current health problems and their weight loss goals. It’s essential to follow the treatment plan and not stop taking the medicine without first talking to a doctor. If you do, you could gain weight.

Who Should Consider Semaglutide for Weight Loss?

Semaglutide isn’t suitable for everyone, and there are specific requirements to meet before starting treatment. Here are some basic recommendations:

1. BMI Requirements

Semaglutide can help overweight or obese people with a BMI of 30 or higher lose weight. People with a BMI of 27 or above with a weight-related medical condition such as high blood pressure, type 2 diabetes, or high cholesterol may qualify.

2. Medical Conditions and Exclusions

People who have had severe illnesses in the past, such as pancreatitis, medullary thyroid cancer, liver disease, or multiple endocrine neoplasia syndrome type 2, should not take semaglutide. Pregnant or lactating women shouldn’t take it, as well as people who have serious digestive problems or gastroparesis.

3. Program Participation

For best results and safety, use semaglutide as part of a complete medical weight loss program. This program should include a balanced, calorie-deficient diet and regular exercise. Talking to a primary care doctor is essential to ensure you’re eligible and the treatment plan fits your needs.

When considering semaglutide for weight loss, it’s essential to consider how it might combine with other medicines and whether your insurance covers it. Some insurance companies may not pay for semaglutide because they see it as a lifestyle enhancer, not a necessary medicine.

Related, Medical Weight Loss for Older Adults

Potential Side Effects of Using Semaglutide

Knowing the possible side effects when taking semaglutide to lose weight is essential. The most frequent digestive issues include feeling nauseous, vomiting, having difficulty going to the toilet, experiencing diarrhea, or not wanting to eat. When beginning treatment, these side effects are often the most intense but may subside over time.

Although rare, allergic reactions and injection-site reactions can occur with semaglutide use, necessitating vigilance for any unusual symptoms. When using semaglutide for weight loss, close medical supervision is essential. It will help ensure individuals properly align and manage their health profiles to reduce risks.

Semaglutide Weight Loss Reviews

Most people who have used semaglutide injections have had a positive experience with them. Many people have shed a lot of weight and felt better altogether. Semaglutide, available under brands such as Ozempic, Wegovy, and Rybelsus, boasts an average rating of 7.2 out of 10 from 570 reviews, with 62% of users reporting positive experiences.

The Best Semaglutide Program

If you want a complete and successful semaglutide program, look no further than Prime Health of New Jersey. Our medical facility in East Windsor, NJ, focuses on a holistic approach to weight loss, and semaglutide is a critical component of our program.

One of the program’s distinguishing aspects is the personalized attention it offers. The program kicks off with a thorough medical examination. After that, you will receive personalized nutritional advice. Our doctor may also prescribe FDA-approved weight-loss medications like semaglutide.

Patients receive ongoing support through remote monitoring and periodic meetings to track progress. It maintains their motivation and enables prompt modifications to the treatment plan.

Semaglutide Cost Without Insurance

The cost should be considered when using semaglutide for weight loss, especially for those without insurance. Prime Health of New Jersey charges $216 for semaglutide as part of their medical weight loss program.

This fee covers the cost of the medication and all services associated with its administration. It encompasses both the medication cost and the services provided. These services include personalized medical evaluations, advice on what to eat, and ongoing monitoring to ensure participants have the best and safest results.

The Final Words

If you want to use semaglutide for weight loss, the first thing to do is schedule a consultation with our experts. During the discussion, you could talk about your goals and desires. This first appointment is critical because it lays the groundwork for a treatment plan personalized to your specific health needs and objectives.

Together with our provider, you can create a clear plan for achieving the desired outcomes.

Remember, dropping pounds is a journey that requires commitment, persistence, and professional assistance. If you get the right help and a personalized plan you can reach your weight-loss goals and improve your overall health and well-being.


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Dr. Farhan Malik Primary Care Physician
Dr. Shoaib Malik Primary Care Physician

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